| Date | Location | Result | |
| 03/06/22 | Washington, DC | Col. of Charleston 92, Hofstra 76 | Box score |
| 02/28/22 | Hempstead, NY | Hofstra 89, Col. of Charleston 84 | Box score |
| 02/26/22 | Hempstead, NY | Hofstra 83, William & Mary 67 | Box score |
| 02/24/22 | Hempstead, NY | Elon 81, Hofstra 55 | Box score |
| 02/19/22 | Hempstead, NY | Hofstra 76, Northeastern 73 | Box score |
| 02/15/22 | Elon, NC | Hofstra 97, Elon 64 | Box score |
| 02/12/22 | Newark, DE | Hofstra 80, Delaware 66 | Box score |
| 02/10/22 | Philadelphia, PA | Hofstra 83, Drexel 73 | Box score |
| 02/07/22 | Hempstead, NY | Hofstra 73, UNCW 71 | Box score |
| 02/05/22 | Hempstead, NY | Hofstra 85, James Madison 78 (OT) | Box score |
| 02/03/22 | Hempstead, NY | Towson 78, Hofstra 68 | Box score |
| 01/29/22 | Wilmington, NC | UNCW 78, Hofstra 72 | Box score |
| 01/27/22 | Charleston, SC | Hofstra 76, Col. of Charleston 73 | Box score |
| 01/22/22 | Boston, MA | Hofstra 72, Northeastern 50 | Box score |
| 01/17/22 | Hempstead, NY | Hofstra 71, Drexel 68 | Box score |
| 01/15/22 | Hempstead, NY | Hofstra 82, Delaware 77 | Box score |
| 01/11/22 | Towson, MD | Towson 78, Hofstra 66 | Box score |
| 01/09/22 | Harrisonburg, VA | Hofstra 87, James Madison 80 | Box score |
| 12/29/21 | Williamsburg, VA | William & Mary 63, Hofstra 62 | Box score |
| 12/22/21 | West Long Branch, NJ | Hofstra 77, Monmouth 71 | Box score |
| 12/18/21 | North Little Rock, AR | Hofstra 89, Arkansas 81 | Box score |
| 12/12/21 | Hempstead, NY | Hofstra 102, John Jay 51 | Box score |
| 12/08/21 | Stony Brook, NY | Stony Brook 79, Hofstra 62 | Box score |
| 12/04/21 | Hempstead, NY | Hofstra 88, Bucknell 69 | Box score |
| 12/01/21 | Hempstead, NY | Hofstra 81, Princeton 77 | Box score |
| 11/27/21 | Hempstead, NY | Hofstra 98, Detroit Mercy 84 | Box score |
| 11/24/21 | Hempstead, NY | Hofstra 87, Molloy 49 | Box score |
| 11/22/21 | Richmond, VA | Richmond 81, Hofstra 68 | Box score |
| 11/19/21 | College Park, MD | Maryland 69, Hofstra 67 | Box score |
| 11/16/21 | New Rochelle, NY | Iona 82, Hofstra 74 | Box score |
| 11/13/21 | Pittsburgh, PA | Hofstra 73, Duquesne 63 | Box score |
| 11/09/21 | Houston, TX | Houston 83, Hofstra 75 (OT) | Box score |